Latest News - Clinical Trials

Thursday, June 22, 2017 | Clinical Trials

Nemus Bioscience Reports on Impact of NB1111 on Tissues that Regulate IOP in an Animal Normotensive Ocular Model

Nemus Bioscience announced that tetrahydrocannabinol (THC) derived from NB1111, the proprietary Nemus prodrug of THC, achieved significant tissue concentrations in multiple compartments of the eye tha…

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Thursday, June 22, 2017 | Clinical Trials, Retina

RXi Pharmaceuticals Announces Completion of Enrollment of Phase 1/2 Clinical Trial with RXI-109 for Retinal Scarring

RXi Pharmaceuticals announced the completion of enrollment in its phase 1/2 study RXI-109-1501. This multicenter, multidose, dose escalation trial is being conducted in patients with advanced neovascu…

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Wednesday, June 21, 2017 | Clinical Trials, Glaucoma, Glaukos Corporation

Study: Combining Implantation of Glaukos iStent inject with Topical Travoprost Provides Sustained IOP Reduction and Favorable Safety Profile

Glaukos announced that a study of 53 open-angle glaucoma subjects recently published in Clinical & Experimental Ophthalmology showed that the iStent inject Trabecular Micro-Bypass, combined with t…

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Tuesday, June 20, 2017 | Clinical Trials, Novartis

Novartis RTH258 (Brolucizumab) Demonstrates Robust Visual Gains in Wet AMD Patients with a Majority on a 12-week Injection Interval

Novartis reported that RTH258 (brolucizumab) 6 mg met the primary and key secondary endpoints in two phase 3 studies, HAWK and HARRIER. RTH258 3 mg, evaluated in HAWK, also met these endpoints. These …

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Tuesday, June 20, 2017 | Clinical Trials

Neurotech Announces Positive Phase 2 Results in NT-501 (CNTF) for Macular Telangiectasia

Neurotech Pharmaceuticals, in collaboration with the Lowy Medical Research Institute (LMRI), announced 24-month results demonstrating that NT- 501 delivering Ciliary Neurotrophic Factor (CNTF) has a b…

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Monday, June 19, 2017 | Clinical Trials, BioTime

Biotime Expands & Advances Ophthalmology Portfolio

BioTime reported several developments for its ophthalmology portfolio, including: Signing a new and expanded licensing agreement with Hadassah Medical Organization of Jerusalem, Israel Present…

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Wednesday, June 14, 2017 | Clinical Trials, GenSight Biologics

GenSight Biologics Reports Long-Term Results in Phase 1/2 Study of GS010 for the Treatment of Leber’s Hereditary Optic Neuropathy

GenSight Biologics reported additional promising clinical trial results with GS010 after 96 weeks of follow-up in its phase 1/2 study. These results confirm the long-term positive sustained visual acu…

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Wednesday, June 14, 2017 | Clinical Trials, Omeros

FDA Grants Breakthrough Therapy Designation to Omeros’ MASP-2 Inhibitor OMS721 for the Treatment of IgA Nephropathy

Omeros announced that the FDA has granted breakthrough therapy designation to OMS721 for the treatment of Immunoglobulin A (IgA) nephropathy. OMS721 is Omeros’ lead human monoclonal antibody tar…

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Tuesday, June 13, 2017 | Clinical Trials, Psivida

pSivida’s Durasert 3-year Treatment for Posterior Segment Uveitis Achieves Primary Efficacy Endpoint

A second phase 3 trial of pSivida's Durasert 3-year treatment for posterior segment uveitis achieved the trial’s primary endpoint. The study involved 153 patients and the primary endpoint wa…

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Monday, June 12, 2017 | Clinical Trials, Conferences

Verseon to Reveal Preclinical Results on Novel Drug Candidates in Diabetic Macular Edema Program at BIO 2017

Verseon will be presenting results from its most advanced drug programs at the 2017 BIO International Conference, held June 19 -- 22, 2017 in San Diego. Dr. David Kita, Vice President of R&D at Ve…

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Sunday, June 04, 2017 | Clinical Trials

Aldeyra Therapeutics Announces First Patient Enrolled in Noninfectious Anterior Uveitis Phase 3 Clinical Trial

Aldeyra Therapeutics announced that it has enrolled the first patient in a phase 3 clinical trial of topical ocular ADX-102 for the treatment of noninfectious anterior uveitis (NAU). "Based on…

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Thursday, June 01, 2017 | Clinical Trials, Avedro

Results From Avedro's Landmark Corneal Collagen Cross-Linking Pivitol Phase 3 Keratoconus Studies Published

Avedro announced the publication of 1-year safety and efficacy data from the randomized, controlled pivotal phase 3 clinical trials that supported the FDA approval of Avedro’s Photrexa Viscous (…

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Wednesday, May 31, 2017 | Clinical Trials, Dry Eye

Lamellar Biomedical Recruits First Patients into Clinical Study Assessing Lamelleye for Treatment of Dry Eye Disease

Lamellar Biomedical announced the recruitment of the first patients in a clinical study assessing Lamelleye for the treatment of moderate to severe dry eye disease (DED). Lamelleye is designed to prov…

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Wednesday, May 24, 2017 | Clinical Trials, Aerie Pharmaceuticals

Aerie Pharmaceuticals Reports Positive Phase 3 Topline Efficacy Results for Roclatan

Aerie Pharmaceuticals reported the successful primary efficacy results of the company’s 90-day, phase 3 Mercury 2 registration trial for its fixed-dose combination product candidate, Roclatan. T…

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Tuesday, May 23, 2017 | Clinical Trials

Dompé Receives Positive CHMP Opinion in Europe For Oxervate for the Treatment of Adult Patients with Moderate or Severe Neurotrophic Keratitis

Dompé has announced that the Committee for Human Medicinal Products of the European Medicines Agency (EMA) has released a positive opinion, recommending the marketing authorization for Oxervate…

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