OMDI as an Alternative to Prostaglandin Analogues in Low or Nonresponders

Joseph F. Panarelli, MD; and Neda Shamie, MD

Eyetube

Joseph F. Panarelli, MD, sits down with Neda Shamie, MD, to discuss a phase 3, nonrandomized, two-phase, open-label, multicenter study that evaluated the IOP-lowering efficacy and safety of omidenepag isopropyl (OMDI) in patients with primary open-angle glaucoma or ocular hypertension who did not respond or responded poorly to latanoprost. What were the results? To access the full review, please visit the link here: https://pubmed.ncbi.nlm.nih.gov/37853676/

The Future of Hyperopic LASIK: Debates and Advances

William F. Wiley, MD, and Wesam Silk, MD

Eyetube

In this episode of CRST: The Podcast, host William F. Wiley, MD, and Wesam Silk, MD, take a deep dive into the evolving world of hyperopic LASIK and its alternatives. They explore the technological advances that have reshaped the treatment of hyperopia, examine the shift toward lens-based solutions, and speculate about future innovations in refractive surgery. 

A Reference Guide for OCT Angiography

An illustrative overview of OCTA findings to help you implement this tool in common clinical scenarios.

Ivy Zhu, MD; Nicole L. Decker, BS; and Amani A. Fawzi, MD

Retina Today

AT A GLANCE OCT angiography (OCTA) has several advantages over traditional imaging techniques, including being noninvasive, depth resolved, and rapid. OCTA can distinguish the various vascular networks without obscuration by leakage, making it helpful for characterizing neovascularization and nonperfusion. OCTA is particularly useful in cases of type 1 neovascularization, where sub-retinal pigment epithelium neovascularization can develop without active exudation. En face OCTA and OCT B-scans are complementary and, together, can provide the clinician with a wealth of knowledge. There are several conditions for which OCTA can provide detailed information that would otherwise be time-consuming or impossible to find with traditional techniques. OCT angiography (OCTA) is a noninvasive imaging technique that uses the principles of motion detection to reveal depth-resolved images of the retinal and choroidal vasculature, down to the capillary level.1 OCTA has several advantages over traditional imaging techniques, including being noninvasive (no dye injection), depth resolved, and rapid. A key benefit of OCTA is its ability to distinguish the various vascular networks without obscuration by leakage, making it very helpful for characterizing retinal neovascularization and nonperfusion with precision beyond dye-based angiography. Here, we detail several clinical scenarios in which OCTA can be a useful diagnostic tool and illustrate key imaging features. In general, absence of flow (nonperfusion) is best appreciated with en face images. The presence of abnormal flow is most accurately detected using a combination of en face imaging assisted by the OCT B-scan with flow overlay to pinpoint abnormal flow related to structural pathological changes.